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Dr. Russell Blaylock: Vaccine May Be More Dangerous Than Swine Flu

http://socioecohistory.wordpress.com/2009/07/15/dr-russell-blaylock-vaccine-may-be-more-dangerous-than-swine-flu/

What the good doctor say is true. Don’t be taken for a ride. So what if you catch this mild 3-4 days flu. It is even weaker than seasonal flu. We need to counter all the MSM propaganda BS that we should look to vaccines to save us! Dr Blaylock writes :

An outbreak of swine flu occurred in Mexico this spring that eventually affected 4,910 Mexican citizens and resulted in 85 deaths. By the time it spread to the United States, the virus caused only mild cases of flu-like illness.

Thanks to air travel and the failure of public health officials to control travel from Mexico, the virus spread worldwide. Despite predictions of massive numbers of deaths and the arrival of doomsday, the virus has remained a relatively mild disease, something we know happens each year with flu epidemics.

Worldwide, there have only been 311 deaths out of 70,893 cases of swine flu. In the United States, 27,717 cases have resulted in 127 deaths. Every death is a tragedy, but such a low death rate should not be the basis of a draconian government policy.

It is helpful to recall that the Centers for Disease Control with the collusion of the media, constantly tell us that 36,000 people die from the flu each year, a figure that has been shown to be a lie. In this case, we are talking about 300 plus deaths for the entire world.

This virus continues to be an enigma for virologists. In the April 30, 2009 issue of Nature, a virologist was quoted as saying,“Where the hell it got all these genes from we don’t know.” Extensive analysis of the virus found that it contained the original 1918 H1N1 flu virus, the avian flu virus (bird flu), and two new H3N2 virus genes from Eurasia. Debate continues over the possibility that swine flu is a genetically engineered virus.

Naturally, vaccine manufacturers have been in a competitive battle to produce the first vaccine. The main contenders have been Baxter Pharmaceuticals and Novartis Pharmaceuticals, the latter of which recently acquired the scandal-ridden Chiron vaccine company. Both of these companies have had agreements with the World Health Organization to produce a pandemic vaccine.

The Baxter vaccine, called Celvapan, has had fast track approval. It uses a new vero cell technology, which utilizes cultured cells from the African green monkey. This same animal tissue transmits a number of vaccine-contaminating viruses, including the HIV virus.

The Baxter company has been associated with two deadly scandals. The first event occurred in 2006 when hemophiliac components were contaminated with HIV virus and injected in tens of thousands of people, including thousands of children. Baxter continued to release the HIV contaminated vaccine even after the contamination was known.

The second event occurred recently when it was discovered that Baxter had released a seasonal flu vaccine containing the bird flu virus, which would have produced a real world pandemic, to 18 countries. Fortunately, astute lab workers in the Czech Republic discovered the deadly combination and blew the whistle before a worldwide disaster was unleashed.

Despite these two deadly events, WHO maintains an agreement with Baxter Pharmaceuticals to produce the world’s pandemic vaccine. Novartis, the second contender, also has an agreement with WHO for a pandemic vaccine. Novartis appears to have won the contract, since their vaccine is near completion. What is terrifying is that these pandemic vaccines contain ingredients, called immune adjuvants that a number of studies have shown cause devastating autoimmune disorders, including rheumatoid arthritis, multiple sclerosis and lupus.

Animal studies using this adjuvant have found them to be deadly. A study using 14 guinea pigs found that when they were injected with the special adjuvant, only one animal survived. A repeat of the study found the same deadly outcome.

So, what is this deadly ingredient? It is called squalene, a type of oil. The Chiron company, maker of the deadly anthrax vaccine, makes an adjuvant called MF-59 which contains two main ingredients of concern—squalene and gp120. A number of studies have shown that squalene can trigger all of the above-mentioned autoimmune diseases when injected.

The MF-59 adjuvant has been used in several vaccines. These vaccines, including tetanus and diphtheria, are the same vaccines frequently associated with adverse reactions.

I reviewed a number of studies on this adjuvant and found something quite interesting. Several studies done on human test subjects found MF-59 to be a very safe immune adjuvant. But when I checked to see who did these studies, I found—to no surprise—that they were done by the Novartis Pharmaceutical Company and Chiron Pharmaceutical Company, which have merged. They were all published in “prestigious” medical journals. Also, to no surprise, a great number of studies done by independent laboratories and research institutions all found a strong link between MF-59 and autoimmune diseases.

Squalene in vaccines has been strongly linked to the Gulf War Syndrome. On August 1991, Anthony Principi, Secretary of Veterans Affairs admitted that soldiers vaccinated with the anthrax vaccine from 1990 to 1991 had an increased risk of 200 percent in developing the deadly disease amyotrophic lateral sclerosis (ALS), also called Lou Gehrig’s disease. The soldiers also suffered from a number of debilitating and life-shortening diseases, such as polyarteritis nodosa, multiple sclerosis (MS), lupus, transverse myelitis (a neurological disorder caused by inflammation of the spinal cord), endocarditis (inflammation of the heart’s inner lining), optic neuritis with blindness and glomerulonephritis (a type of kidney disease).

Because squalene, the main ingredient in MF-59, can induce hyperimmune responses and induce autoimmunity, a real danger exists for prolonged activation of the brain’s immune cells, the microglia. This type of prolonged activation has been strongly associated with such diseases as multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, ALS and possibly vaccine-related encephalitis. It has been shown that activation of the systemic immune system, as occurs with vaccination, rapidly activates the brain’s microglia at the same time, and this brain inflammation can persist for long periods.

So, how would the gp120 get into the brain? Studies of other immune adjuvants using careful tracer techniques have shown that they routinely enter the brain following vaccination. What most people do not know, even the doctors who recommend the vaccines, is that most such studies by pharmaceutical companies observe the patients for only one to two weeks following vaccination—these types of reactions may take months or even years to manifest.

It is obvious that the vaccine manufacturers stand to make billions of dollars in profits from this WHO/government-promoted pandemic. Novartis, the maker of the new pandemic vaccine, recently announced that they would not give free vaccines to impoverished nations—everybody pays.

One must keep in mind that once the vaccine is injected, there is little you can do to protect yourself—at least by conventional medicine. It will mean a lifetime of crippling illness and early death.

There are much safer ways to protect oneself from this flu virus, such as higher doses of vitamin D3, selective immune enhancement using supplements, and a good diet.



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23 comments for “Dr. Russell Blaylock: Vaccine May Be More Dangerous Than Swine Flu”

  1. “It is obvious that the vaccine manufacturers stand to make billions of dollars in profits from this WHO/government-promoted pandemic.”

    Yes, and they might even send the troll and his family to a luxury resort area for a couple of weeks. Imagine if he was too busy to spam this site for 2 weeks!

    Gary the spammer troll (and his aliases) will be sure to plague this discussion thread with their trollfoolery, spam, and establishment medicine drivel.

    As usual, the truth presented by Dr. Blaylock will have no effect on the “vaccine-addled” troll and his imaginary friends.

    Scott’s words yesterday to “alex search” apply equally to Gary the spammer troll:

    “You are either a paid liar, an idiot, or both.” Posted by ewingsc | July 31, 2009, 12:05 pm

    “Health and Nutrition Secrets: that can save your life” By Russell L. Blaylock, M.D.

    This book brings together a wealth of information from a variety of authoritative sources. The author, Dr. Russell Blaylock, explains how you and your family can stay healthy and avoid some pitfalls of modern living.

    Dr. Blaylock contends that though we may be “wired” for certain conditions as we age, good nutrition and healthy living can do a lot to waylay, and sometimes prevent, the activation of genetic switches that are linked to the most dreaded diseases of aging.

    The first section deals with the most harmful, and seemingly unavoidable, environmental toxins we encounter on a regular basis (increasingly unhealthy food, pesticides and other industrial chemicals, and heavy metals) and the biochemical reactions that trigger the advent of disease.

    Dr. Blaylock asserts that the profusion of strong drugs routinely prescribed for unsuspecting Americans frequently causes more harm than good–especially when benign natural treatments can accomplish much more in terms of actual healing, and usually for less money. He includes a scathing indictment of the politics of the pharmaceutical industry’s profit machine.

    In his first book, Excitotoxins: The Taste that Kills Dr. Blaylock made the connection between food additives (in particular, Monosodium Glutamate and Aspartame) and degenerative diseases of the nervous system–Alzheimer’s, Parkinson’s, and ALS. Citing new studies, Chapter Seven of this book revisits the increasingly inescapable relationship of food chemistry and degenerative disorders.

    The second section is concerned with the diseases that most of us will eventually encounter as we age, including atherosclerosis, heart attack and stroke, osteoporosis, and diabetes. Chapter Twelve, “Protecting Your Brain,” is specifically concerned with the prevention and and diagnosis of degenerative nervous-system diseases.

    Each chapter addresses what systems of the body are affected by each disorder, discusses the healthy operation of the physical systems involved, and explains what goes wrong when disease occurs. He also provides fascinating current theories about the causes of each disorder, and easy-to-implement alternatives to “big” medicine’s treatments for many of these diseases.

    In addition, Dr. Blaylock challenges misplaced notions of physical “fitness” and highlights the small changes that can have a huge impact on healthy aging. For instance, citing numerous fitness and diet studies, Dr. Blaylock dispels the idea that aerobic exercise is the best way to achieve physical fitness; in fact, he demonstrates that aerobic exercise may actually be quite harmful for many segments of the population. He suggests alternatives, such as walking and isometric exercises, to achieve a healthy physical balance.

    Included with each discussion of a specific health danger is a comprehensive set of recommendations for avoidance, prevention, and improvement, enabling readers to take an active, well-informed role in their own medical care and overall well-being.

    http://radioliberty.com/bhans.html

    Russell L. Blaylock, M.D. quotes http://www.whale.to/a/blaylock_q.html

    AN INTERVIEW WITH DR. RUSSELL BLAYLOCK http://www.whale.to/v/Aspartame_Truth.pdf

    THE TRUTH BEHIND THE VACCINE COVER-UP http://www.whale.to/a/blaylock.html

    http://www.russellblaylockmd.com/

    Posted by Philip | August 1, 2009, 4:51 am
  2. Hi I would just like to point out that bill is a person called mitchal heslip who is a border at john mcglashan collage if you would like to contact him to abuse him of his comments please contact him at john mcglashan

    Posted by Bill2.0 | August 3, 2009, 7:17 pm
  3. Bill2.0, please learn some basic punctuation. Without it you appear even dumber than an anti-vaccer!

    Posted by Gnome, Troll or otherwise | August 3, 2009, 11:38 pm
  4. Could the citizens who don’t want the swine flu vaccine begin a class action lawsuit against WHO and all others involved demanding we at least be given a complete vial containing enough of the serum we are to be injected with to have it independently tested for safty if we are being forced to receive it? Hell, we know they are trying to kill as many of us as they can and there has to be some recourse we can take. With the past record of these flu vaccines only a fool would want their loved ones injected with the government poison. We must find some way to fight them. If we are willing to pay for the serum I don’t know how they could refuse us if there are enough to request it by class action.

    Posted by Becky | August 12, 2009, 5:47 pm
  5. “The greatest lie ever told is that vaccines are safe and effective” – Dr. Len Horowitz

    http://whale.to/vaccine/quotes21.html

    ___________________________________

    Find out why trusted vaccines, blood supplies, and drugs play a primary role in what amounts to genocide for profit, psychosocial control, and even depopulation. We urge you to make copies of this exceptional 45-minute presentation, help spread this recording, and stop the killing.

    http://www.americanreddoublecross.com/news/massmurderinmedicine.html

    ___________________________________

    “Delay of DPT immunisation until 2 years of age in Japan has resulted in a dramatic decline in adverse side effects. In the period of 1970-1974, when DPT vaccination was begun at 3 to 5 months of age, the Japanese national compensation system paid out claims for 57 permanent severe damage vaccine cases, and 37 deaths. During the ensuing six year period 1975-1980, when DPT injections were delayed to 24 months of age, severe reactions from the vaccine were reduced to a total of eight with three deaths. This represents an 85 to 90 percent reduction in severe cases of damage and death.” – Raymond Obomsawin, M.D.

    http://www.vaclib.org/basic/quotes.htm

    http://www.vaclib.org/chapter/inserts.htm#human

    http://www.vaclib.org/toc.htm#ingredients

    Posted by Philip | August 13, 2009, 10:16 am
  6. “Hell, we know they are trying to kill as many of us as they can and there has to be some recourse we can take.”

    WHAT? How stoopid can you be Becky? The best way to kill dumb bastards like you is NOT to give you vaccines and let you die from disease.

    Use the few brain cells you have left and get to a real doctor for your vaccinations.

    Regards
    Gary

    Posted by Troll | August 13, 2009, 11:42 am
  7. “Hell, we know they are trying to kill as many of us as they can and there has to be some recourse we can take.”

    They’re doing a pretty shite job about it then. Let’s face it, every year there is the “uncovering” – by such experts as Alex Jones, David Icke and the like – of a new Illuminati plot to kill most of the world’s population, and every year these predictions turn out to be a damp squib. All those FEMA subcontractors promised juicy positions exterminating the populace in NWO concentration camps must be in the process of filing lawsuits against their local Illuminati representatives as we speak. Oh well, the ‘truther’ community have still got chemtrails, ‘forced vaccinations’, and the 2012 comet impact to keep soiling their paranoid pants over.

    Posted by alex search | August 13, 2009, 2:51 pm
  8. What complete and utter drivel you talk alex search (so does the troll but then that goes without saying). If ever there was proof of someone with just enough knowledge to be completly ignorant you are a perfect example.

    David Icke has been researching this topic for over 20 years and has written about things that ARE happening now that won’t even thought of back then. If you are too thick to be able to see put it all together that is your problem.

    As for the last statement well in all truth aren’t you the one who soils your pants everytime someone dares mention the disgusting facist behaviour of the Zionists.

    Get a life you worm.

    Posted by Lorraine | August 13, 2009, 4:13 pm
  9. “alex search” again riding shotgun beside the other troll (Gary).

    Couldn’t wait to chime in after that vicious post at 11:42 am.

    The troll and the Israeli mole team up to ridicule the better informed one more time.

    Notice how the troll’s hateful comments toward Becky draws the mole out of his crevice to spew his hatred of the truth again.

    You hit another low, Gary / troll, with your venomous rant above.

    You are the “dumb bastard” posting here; and another round of Big Pharma’s life-transforming vaccines will not change that fact.

    What to do with the troll?

    Click here: http://www.ringling.com/OpenClownCannon.aspx?&parentID=390&assetFolderID=394

    ___________________________________

    Lorraine’s assessment…

    “If ever there was proof of someone with just enough knowledge to be completely ignorant you are a perfect example.”

    …pins the mole to the wall one more time!

    Poor Israeli mole

    :(

    Outgunned – misinformed – too numb to stop what he’s doing.

    ___________________________________

    Posted by Philip | August 14, 2009, 7:06 am
  10. From the Dumb Ass series:
    “7. The vaccine is worse than the disease. Dumb ass AND a wimp. What a combination. Your mother must be proud. Unless you think a sore deltoid for a day is too high a price to pay to prevent two weeks of high fevers, severe muscles aches, and intractable cough.”

    http://boards.medscape.com/for….soMda7z9d9K@.29f60079!comment=1

    Posted by Troll | September 25, 2009, 12:32 pm
  11. Gary, I bet when you were a child you stood on the playground shoving pebbles up your nose just to get attention. Your parents probably had to tie a porkchop around your neck to get the family dog to play with you.

    It is sad to see people who never have a sensible contribution to any forum and try to make up for it by being the ‘class’ fool in the dunce cap. Congratulations, you haven’t lost your touch.

    Posted by Becky | September 25, 2009, 1:56 pm
  12. “Gary, I bet when you were a child you stood on the playground shoving pebbles up your nose just to get attention. Your parents probably had to tie a porkchop around your neck to get the family dog to play with you.”

    Better than being the equivalent of some ranting wide-eyed nutter marching up and down the streets wearing a sandwich board bearing the phrase ‘the end is nigh’, which pretty much describes the conspiracy theorists featured on this site…

    Posted by alex search | September 25, 2009, 2:22 pm
  13. Alex, run along now, Gary said you could wear his porkchop for a few days.

    Posted by Becky | September 25, 2009, 2:30 pm
  14. whoops, the family dog and I just did a mess on your doorstep…you forgot to put the plastic bottles on the lawn!

    Posted by alex search | September 25, 2009, 3:18 pm
  15. Wow Alex, did you think that up all by your little bitty self?!! How very adult but your potty training seems to be lacking. Run along, they are waiting for you at the group home with all your pretty meds.

    Posted by Becky | September 25, 2009, 3:26 pm
  16. “Alex, run along now, Gary said you could wear his porkchop for a few days.” Brilliant, well thats my vote for ‘comeback of the year’ … and it works on so many levels.

    Posted by lombeer | September 26, 2009, 12:04 am
  17. Ate my chop. Yum. It was not inorganic.

    So Becky, tell us how your parents made you wear tin foil hats to keep the government from controlling your brain. And don’t leave out the bit about everyone teasing you in the playground. I hope you enjoy living next to a cel phone tower. Opps! didn’t they tell you? They are starting construction in a few months. Damn, it must be another conspiracy.

    Posted by Troll | September 26, 2009, 10:24 am
  18. I would like to point out that I no longer associate with Gary, or Alex.

    Posted by The Porkchop | September 26, 2009, 10:44 am
  19. I would like to point out that I no longer associate with the pork chop.

    Posted by The Apple Sauce | September 26, 2009, 11:01 am
  20. Damn you Apple Sauce ! I knew I hadn’t seen the last of you !

    Posted by The Porkchop | September 26, 2009, 11:20 am
  21. US: Most parents now say they will not have their kids vaccinated against Swine Flu.
    LA Times 2009 Sept 25

    http://www.latimes.com/news/nationworld/nation/la-sci-parents-flu25-2009sep25,0,579663.story

    Germ-spreading schoolchildren are expected to be the focus of a massive U.S. vaccination campaign against the novel H1N1 flu.

    But if their parents are hearing the rallying cry to have their kids vaccinated, they’re not buying it, says a new national survey.

    In a poll of 1,678 U.S. parents conducted by the University of Michigan’s C.S. Mott Children’s Hospital, 40% said they would get their children immunized against the H1N1 virus — even as 54% indicated they would get their kids vaccinated against regular seasonal flu.

    Among those who said they do not intend to have their kids vaccinated against H1N1, almost half — 46% — indicated they’re not worried about their children becoming ill with the pandemic virus. Twenty percent said they do not believe the H1N1 flu is a serious disease.

    There were differences along racial and ethnic lines in parents’ responses, which were collected Aug. 13 to Aug. 31. More than half of Latino parents said they would bring their kids to get vaccinated against H1N1. Among white parents, 38% said they would do so. African American parents were the least inclined to vaccinate: 30% said they planned to do so.

    About half of the parents who said they’d pass on the H1N1 flu shot for their kids expressed concern about possible side effects of the vaccine.

    The chatter about seasonal flu and novel H1N1 flu, and the differences in their relative virulence, has certainly confused parents, the survey suggests. Half of respondents said they believe that, for children, seasonal and H1N1 flu pose roughly equivalent risks.

    “That perception may not match the actual risks,” Dr. Matthew Davis, the poll director, said in a statement. Davis is a University of Michigan professor of pediatrics and internal medicine.

    The Centers for Disease Control and Prevention has said that though serious complications of seasonal flu appear to spare most kids and strike the elderly and very young most heavily, the novel H1N1 flu appears to hit children and young adults hardest.

    Not surprisingly, parents who believe that the H1N1 flu will be worse for children were most likely to say they will have their own children vaccinated.

    In a news release accompanying the poll results, Davis said that public health officials wishing to maximize vaccination rates among schoolchildren need to communicate clearly to their parents that kids are at relatively greater risk of becoming seriously ill with the novel flu strain if they get it.

    Posted by I Am You | September 26, 2009, 1:30 pm
  22. “US: Most parents now say they will not have their kids vaccinated against Swine Flu.”

    Great news for those who want to see a population decrease next year.

    Posted by Troll | September 27, 2009, 9:19 am
  23. “Flu season is upon us (it kind of never left us this year), and there is a new strain of flu, the H1N1, aka Swine flu that adds a wrinkle or two to the usual potential for influenza related morbidity and mortality. And with the new flu is the new woo. I know that others have addressed flu in this forum and some of this may be redundant. Still, we each have our different styles and interests, so I hope the various posts are additive rather than redundant. I am going to wander through some odds and ends about flu in general and H1N1 specifically and compare some of the woo with the reality. At least my reality.

    Influenza and Vitamin D

    Influenza can be prevented or treated with Vitamin D. Don’t tell that to Dr. Marshall. The Natural News, the source for all things over hyped and under understood (Ick. That parallel form didn’t work.), is a nice example of the hype of Vitamin D as a preventative an treatment of influenza.

    Vitamin D is an interesting molecule. Besides its long known effects on bone metabolism, Vitamin D has many immunomodulatory effects and is an important vitamin for immune function. Vitamin D even has effects on nitric oxide regulation. Its effects on infection risks are just beginning to be elucidated but deficiency states (note deficiency states) are associated with an increased risk of viral respiratory infections and worsening of pulmonary tuberculosis.

    Again, deficiency states. If you are replete in your Vitamin D, there is apparently no immunologic advantage in taking extra, as seems to be the case with all vitamins. Metaphorically, if the tank is full of gas, you can’t go further by pumping more gas into the tank.

    Vitamin D deficiency is not uncommon in the Northern Latitudes especially in the winter and in populations who have little sun exposure (nursing home patients). So like all deficiency states, it is reasonable to fill the tank, with extra Vitamin D. It will probably decrease the chance of getting a viral respiratory infection. In general, supporting data is limited and the effect small, as a review points out (2).

    How about Vitamin D specifically for influenza?

    There, the data is limited and mostly epidemiologic, but interesting none the less. The natural news, which states “In the realm of peer-reviewed medical literature, searching Google Scholar for “influenza” and “vitamin D” returns tens of thousands of results (http://scholar.google.com/scholar?q…).”

    Interestingly, using influenza and dental floss for search terms on Google scholar results in over 1500 articles; it is hardly the source for the peer reviewed literature. If you use Pubmed, the source for peer reviewed literature, there are 30 references, not tens of thousands, and less than a half dozen specifically concerning vitamin D and influenza.

    The reasoning goes like this: flu increases in the winter. In the winter people get less sunshine and their vitamin d levels drop. Therefore it is the vitamin d deficiency in the winter that predisposes to influenza. Of course, people crowd together inside in the winter, increasing ease of transmission and flu occurs in the tropics where it is always sunny, so it is probably not the only reason flu increases in the winter. But it may well be a small component,

    It is biologically plausible that vitamin deficiency increases your risk for infection, there is reasonable epidemiologic data to support the association, and it is not unreasonable to be replete in you vitamins.

    What is neither reasonable nor supported is to take supratherapeutic amounts of vitamin D as a replacement for either the vaccine or, if you should get flu, oseltamivir.

    Vitamin D is not ” is perhaps the single most powerful nutrient in the known universe for preventing influenza, ” despite the Natural News hysterics. Yet another alternative mountain made from a scientific molehill.

    SURVIVAL OF THE FITTEST

    Use of the vaccine is counterproductive. Use of the vaccine will lead to a superbug.

    I have found this on the webs and from a letter to SBM, and I can only speculate where this idea originates.

    Antibiotics can breed resistant bacteria and resistant organisms are often referred to a superbugs. The resistant organisms may not necessarily be more virulent. Just because the bacteria may be harder to kill with antibiotics doesn’t necessarily mean it is more invasive. Sometimes, like current strain of methicillin resistant staphylococcus, may also has a high incidence of carrying genes that increase its virulence. However, as best I can tell, the increased virulence genes of the USA 300 strain are independent of its antibiotic resistance.

    There was an interesting report in Clinical Infectious Diseases that suggests that as a result of anti retrovirals, perhaps HIV is becoming more virulent. It can happen as a result of antibiotics, but it is unpredictable.

    Certainly if you markedly decrease a pathogen in the community, those who would have died in the past are more likely to survive and pass on their susceptibility to their offspring, increasing the vulnerability of the population to the severe disease. Put’ toll’, ‘infection’ and ‘polymorphism’ into Pubmed to find a growing literature on the genetic susceptibility for getting and dying from various infections. Historical epidemiology out of Utah suggests that the risk of death from influenza is inheritable.

    So what you might expect is after long term vaccine use allows for the accumulation of susceptible hosts in a population and if there is a decline in vaccine use that there will be an increase in morbidity and mortality when the disease returns to a more susceptible population. So it may not be due to a superbug, but a susceptible population; increase in death due less to the organism and more to the host.

    So can vaccine induced immunity lead to a superbug? It has not yet happened, but it does have some plausibility and it depends on the virus. Widespread use of smallpox vaccine did not lead to a super-small pox, it lead to the eradication of small pox. But, some viruses, due to sloppy reproduction, as occurs in influenza, can alter their surface proteins (where antibodies bind) to escape the immune system. So widespread use of the vaccine could (and should?) lead to new strains of influenza that avoid the antibody. But, and here is the key thing, that happens with normal infection.

    As the flu season progresses the organism slowly changes its surface proteins (aka genetic shift) so that the strain at the end of the season is different than the strain at the beginning of the season, part of why we need a new vaccine every year. However, these mutations as a rule do not make the organism more virulent. That usually requires both a genetic shift (new genes) and bad luck (the organism getting the ‘right’ new genes) and this process is not affected by immunity. So it seems unlikely that widespread use of the vaccine would lead to a superbug. So you can potentially put immunologic pressure on influenza to change two ways: my getting the vaccine or by getting the flu. Both will lead to antibody against the organism, but only one will make you sick and potentially pass the infection on to others. But the end result will be the same.

    A NEW WORLD ORDER

    There is this weird paranoid thread running through the internet that the government simultaneously wants widespread use of the vaccine to line the pockets of doctors and big pharma, and to control health care costs by releasing a laboratory derived influenza culling the ill who cost society the most, and to cause widespread panic so that the UN can take over the US and install a new world order.

    H1N1 is not going to be a very good way to either decrease costs or to cull the most susceptible.

    First, H1N1 is highly infectious but not particularly virulent. While the 1919 H1N1 killed maybe 5% of the population, the current H1N1 has a mortality rate of 0.6%. Since this is based on hospitalized cases, the true death rate is probably much less. The groups most at risk of dying from H1N1 are those less than 60 and healthy. So if you were trying control costs by killing the most at risk, this is wrong strain of flu. Not only is it relatively non fatal, it kills off those who have little impact on health costs and causes widespread morbidity, only increasing costs. Of course, the government is incompetent, so leave it to them to do it all wrong.

    As the Chair of our Infection Control committee, the hospital bylaws give me, in case of emergency, the powers to do anything I damn well please to control infection, including isolating patients, shutting down hospital wings, and sending people home. And I have had the opportunity to do all the above, but never by myself. At least in the hospital we work with consensus. You don’t close a hospital wing lightly.

    States have also long had the power to compel people in infectious disease emergencies. I remember, and I am sure some of you will be appalled, as a resident we had a person with cavitary (read very infectious) tuberculosis who refused medications and was homeless (and crazy). As a public health risk she was basically incarcerated in the hospital and forced to take Tb medications. It was not fun.

    It is an interesting question to what extent the state will compel patients in the case of widespread contagion. Hopefully they will not respond like the Italians to bubonic plague and brick people up in their houses, presumably with a cask of amontillado. It is also the case that our legislators, generally being ignorant of things medical and scientific, will pass stupid laws. Don’t get me started in mandatory MRSA screening.

    I do see the need for these laws as the history of plagues demonstrates that people do not necessarily exhibit their best behavior nor act rationally in an epidemic. Fortunately, as this strain of flu is not usually fatal, calmness will probably prevail and we will not be turning our government over to the UN, although just how this is supposed to occur logistically is never stated.

    FLU WILL MELT MY IMMUNE SYSTEM

    The reason I do not want to call it the swine flu, besides the fact it is not really from swine, is that it hearkens back to 1976 when we last had a ’swine’ flu. (I want to call it the rotting genitals flu, it may make the vaccine more desirable). With that vaccine was a bump in the incidence of Guillain- Barre syndrome (GBS), as disease where the insulation of your nerves falls off, leading to paralysis.

    Not a good disease. Now as I write this on 9/8/9 there have been 598 deaths from H1N1. How many cases of Guillain- Barre syndrome were there in 1978 ? 532 cases that occurred within 5 to 10 weeks of the vaccine in over 40 million vaccinations. Why? No one knows.

    “As of 1976, >50 “antecedent events” had been identified in temporal relationship to GBS, events that were considered as possible factors in its cause. The list included viral infections, injections, and “being struck by lightning.” Whether or not any of the antecedents had a causal relationship to GBS was, and remains, unclear. When cases of GBS were identified among recipients of the swine flu vaccines, they were, of course, well covered by the press. Because GBS cases are always present in the population, the necessary public health questions concerning the cases among vaccine recipients were “Is the number of cases of GBS among vaccine recipients higher than would be expected? And if so, are the increased cases the result of increased surveillance or a true increase?” Leading epidemiologists debated these points, but the consensus, based on the intensified surveillance for GBS (and other conditions) in recipients of the vaccines, was that the number of cases of GBS appeared to be an excess. (ref)”

    Was it the strain of flu? Was it the preparation? Subsequent flu seasons have not seen an increase in GBS. The current H1N1 is genetically distinct from the 1976 strain (ref) and there is no cross protection from the 1976 vaccine. Given the strain difference and the improved production of vaccines, there is probably no reason to worry about increased risk of GBS with this vaccine. Unfortunately we will know for sure until we have given 40 million doses.

    Don’t you love the uncertainty. That’s the problem. I have to deal with uncertainties and probabilities of complex systems. I know the estimates are that for every 1000 people who get H1N1, 40 may end up in the hospital and 1 may die. With 300,000,000 Americans, that’s 30,000 deaths (standard for flu) and 120,000 in the hospital. Compare to 598 cases of GBS and 25 deaths in 1976. About as many as are trampled by cattle each year, but no one is getting rid of steak.

    That’s always a problem. Maybe 800 lives are saved by airbags a year; they kill maybe 20 people a year. Numbers vary. So the greater risk is not having air bags, and like many aspects of life, it is not all or nothing. People expect vaccines to be all or nothing. 100% effective, zero risk. Humans are not good at trying to decide what relative risk is. Odds are far greater that you will get and die from H1N1 than the odds you will die from vaccine related GBS, assuming that the vaccine has the same risk as 1976, about the same risk as being killed by your airbags. But we will not know with certainty until this time 2010. People do not deal well with this kind of uncertainty. As Ed said, “Doctors say that Nordberg has a 50/50 chance of getting the flu, though there’s only a 10 percent chance of that.”

    Public health and influenza vaccines target populations by treating individuals, trying to do the most good for the most number of people. But real effects of influenza vaccination are on populations, and the more of a population is vaccinated, the better the population does. People miss part of the point when they look at sub groups and say, well, the vaccine only helps the elderly or pregnancy women. It’s the old adage of the rising tide lifting all boats. But my sense is that people are more selfish now than they were back in the last century, being unwilling to have 2 days of a sore arm to potentially prevent spread of a disease that may kill a stranger. Besides, they were old and going to die anyway.

    A NEW AND UNTESTED VACCINE IS BEING TESTED ON THE AMERICAN PUBLIC

    It is new, and it is untested. As the flu vaccine is every year. Or, more appropriately, it’s the same old flu with the same old vaccine. Keeping with the car metaphor used above, we are not seeing a new form of transportation, just a new model of the same old car.

    It takes about 9 month to make a flu vaccine. The first three months or so are spent deciding on what strains are to be included and if there are representative strains that grow well for vaccine production.

    After the strains are chosen, it takes about 6 months to grow up large quantities of vaccine in chicken eggs. Each dose of vaccine comes from one egg. And there is only one chicken that can make all those eggs and she gets tired. Then the vaccine is purified to just the neuraminidase and hemagglutinin proteins that are in the vaccine.

    The fast track we have now is due to a lucky confluence of factors. First, industry had just finished making this years seasonal flu vaccine so they had the unexpected capacity to churn out vaccine. But more importantly they had a jump on picking the strain. They did not have to guess which strains to include, they knew it was H1N1, so that gave them a three month head start. That is the main reason we have the H1N1 vaccine in record time. The process of growing the influenza and purifying it is preceding at the usual pace. We we just lucky that we were able to know the exact strain and it occurred when we had the capacity to make extra vaccine.

    So while it is being produced at a faster rate, it is not because they are skimping on the steps in the production, it is because we got lucky. As an aside, I am told that the strain they are using for the vaccine is not the best at growing in chicken eggs and is a reason the vaccine will not be ready until mid October. Evidently it does not grow as robustly in chicken eggs as they would like.

    As far as anyone can tell, they is nothing special about the H1N1 strain (and they have looked at it closely) to suggest there is anything unique about it except that it is immunologically new (at least since 1950’s, when the H1N1 progenitors were last seen in humans). This H1N1 in part can be traced back to the 1918 strain and explains why those over 60 have a decreased death rate rather than the usual increased mortality from influenza: old people have cross reacting antibodies to the strain that is protective.

    This strain is only new to people born since about 1950, which is billions of people at risk with no immunity. But as far as virulence and antigenicity, it is the same old influenza, re-assorting its RNA to come up with new strains as it has always done and will continue to do as long as there are people pigs and birds around to get influenza.

    H1N1 is fundamentally the same as any other flu that we have been making vaccine against for as long was he have been making vaccine. It is undergoing the same testing we have used every year and there is no reason to suspect that we should be doing otherwise.

    I am nervous. Fall is coming. If H1N1 comes again (and pandemics have swept through the world several times in one year, the 1919 flu may have had three peaks) before the vaccine, we could be in a world of hurt. Not a lot of deaths by US standards (we lose that 30,000 or so to guns or car accidents every year, just like flu). I have spent a career watching people suffer and occasionally die of potentially preventable illnesses. I am not a fan of death by infection. I hope the vaccine is widely available and widely used so that people live to die at a later date by “a parachute not opening… that’s a way to die. Getting caught in the gears of a combine… having your nuts bit off by a Laplander, that’s the way I wanna go!” But I digress.”

    Published by Mark Crislip

    Posted by Troll | September 27, 2009, 9:27 am

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