Part 1 of Stealth Virus, Bacteria and Fungi is here.
Stealth Virus, Bacteria and Fungi
The Vitamin D Receptor is a 423-residue long protein consisiting of two domains: DNA binding
domain and ligand binding domain (LBD), the latter one pictured above. The VDR belongs to the
nuclear receptor (NR) superfamily including receptors for the steroid, retinoid and thyroid hormones.
Dr. Trevor Marshall and others believe that the ability of the Th1 pathogens to proliferate in the body is directly related to the vitamin D receptor (VDR). Critically important to the body, the Vitamin D Receptor (VDR) controls the innate immune system – the body’s first line of defense against infection. The VDR is also responsible for turning on/off a wide array of genes and chemical pathways. Another of the VDR’s myriad jobs is to control expression of several families of antimicrobial peptides (AMPs), proteins that kill bacteria, viruses and fungi by a variety of mechanisms including disrupting membranes, interfering with metabolism, and targeting components of the machinery inside the cell.
Dr. Marshall and associates come up with a very allopathic way of treatment to root out these L bacteria or fungi or whatever pathogen names you want to call them by. But would anyone who has an inclination toward natural medicines want anything to do with the Marshall Protocol of sun and vitamin D deprivation 1 along with long term low dosage antibiotic administrations? Their approach is to totally cut patients off from the sun in a most radical way and to not take any vitamin D supplement to remove pressure on the Vitamin D Receptors and then to treat with a myriad of low dose antibiotics. Their treatments provoke what are experienced as detox reactions during the months and even years the treatments takes, which are explained or rationalized to be yeast or L-bacteria die offs. Dr. Marshall though started out on the exact right point 2 and that is the effort to go right into the heart of cells and to join in battle with the enemy within, infections, colonies of living protein alien to our biology. For certain classifications of patients this is as important as breathing air.
The active form of vitamin D binds to intracellular receptors that then function as transcription factors to modulate gene expression. Like the receptors for other steroid hormones and thyroid hormones, the vitamin D receptor has hormone-binding and DNA-binding domains. The vitamin D receptor forms a complex with another intracellular receptor, the retinoid-X receptor, and that heterodimer is what binds to DNA. In most cases studied, the effect is to activate transcription, but situations are also known in which vitamin D suppresses transcription and this is what the Marshall Protocol of sunlight deprivation seeks to control.
But sunlight triggers formation of antimicrobial peptides, which are potent and broad spectrum antibiotics. Interestingly the factor most associated with increased melanoma risk was the use of sunscreens, which suppresses vitamin D formation and increase toxic loads due to transdermal penetration. Subjects who often used sunscreens had triple the melanoma risk compared with subjects who never used sunscreens. Skin color and higher numbers of sunbaths were significant protective factors. Subjects who took more than 30 sunbaths per year were ten times less likely to have melanoma, compared with subjects who took less than 20 sunbaths per year. However, sunbaths had no protective value when they were associated with sunburns.3
A molecular model comparing the structure of 25-D and of 1,25-D
Based on whole body sufficiency for iodine, the US population is severely deficient in this essential element and that is a factor left out of the Marshall Protocol that is important because iodine plays a role in vitamin D metabolism and has a modulating effect on target organ response to calcitriol, the normal range of serum 25-OH-[D.sub.3] would need re-evaluation in whole body iodine sufficient individuals, according to Dr. Guy E. Abraham and Dr. Jorge D. Flechas. Vitamin D is essentially a steroid and iodine affects receptor responsiveness to estrogens and other steroids.4
Whole body iodine sufficiency has a direct bearing on the conversion of 25-OH-[D.sub.3] to the active hormone calcitriol. These doctors also point out that magnesium increases the 1-hydroxydase activity of the kidney.5 Therefore adequate magnesium intake would lower the serum 25-OH-[D.sub.3] levels required for adequate calcitriol synthesis.6 One would expect a magnesium sufficient individual to achieve normal calcitriol levels with lower serum 25-OH-[D.sub.3] than in a magnesium deficient individual. These doctors have used iodine successfully for the treatment of fibromyalgia (FM) pain and associated discomfort, one of the same diseases that the Marshall Protocol seeks to alleviate.7
Fungi make things. They spit out these chemical mycotoxins as readily as we
exhale carbon dioxide. These toxins can cause cancer, destroy our organs,
alter our immune system, and affect our hormonal balance. There are mycotoxins
that laboratory scientists can inject into animals and cause them to have both Type
1 diabetes and insulin resistance. That information alone is enough to make front-page headlines, yet in which newspaper have you seen this discovery boldly displayed?
Dr. Dave Holland
Normally, candida albicans lives peacefully in our intestines and elsewhere, in harmony with other flora that keep the yeast in check. Take an antibiotic and all this changes. By suppressing the normal flora, candida takes over and problems begin. In its mild form the result is diarrhea or a yeast infection. Dr. Elmer Cranton says that, “Yeast overgrowth is partly iatrogenic (caused by the medical profession) and can be caused by antibiotics and cortisone medications. A diet high in sugar also promotes overgrowth of yeast. A highly refined diet common in industrialized nations not only promotes growth of yeast, but is also deficient in many of the essential vitamins and minerals needed by the immune system. Chemical colorings, flavorings, preservatives, stabilizers, emulsifiers, etc., add more to stress on the immune system.”
Magnesium chloride is the only form of
Mg known to have anti-infectious properties.
The connection between bacteria and calcification in heart disease has already been noted. Researchers at the Hospital Das Clinicas in Brazil found significantly higher concentrations of Chlamydia pneumoniae and Mycoplasma pneumoniae in calcified nodes of blood vessels throughout the body, including the heart and the aorta – causing them to suggest that “these bacteria may be associated with the development of calcification and inflammation.” L-form bacteria in the brain cause the release of cytokines that damage the tissues. Sometimes the resulting inflammation damages blood vessels and promotes calcification, but it is the L-form bacteria, not the calcium that is the true culprit. One has to be very careful when laying blame on minerals. The real problem with calcium is when it is in excess relative to magnesium thus deficient magnesium leads to calcium excess and inflammation.
Iodine is utilized by every hormone receptor in the body.
The absence of iodine causes a hormonal dysfunction that
can be seen with practically every hormone inside the body.
Dr. George Flechas
Over 30 years ago, two ophthalmologists observed that a combination tablet called “Iodo-niacin” (iodide 120 milligrams, niacin 15 milligrams) taken for several months could actually reverse atherosclerotic clogging of arteries. They proved this effect by taking pictures of clogged arteries in the backs of the eyes (retinal photomicrographs) before and after treatment. The published photographs showed a significant lessening of the cholesterol-laden artery clogging in the “after” pictures. Iodine is an anti- inflammatory because it destroys most single cell pathogens and even biofilms on contact. Iodine is an essential mineral important for many crucial components of healthy human physiology so it makes a far better antibiotic, anti fungal and weapon against stealth viruses including L-bacteria or mycoplasmas than pharmaceuticals.
Today we have to change our perceptions about infections and infectious processes. We need to shift away from the competing paradigms of pathogen vs. terrain. We need to deal simultaneously with pathogen, terrain and poison. Mercury provides the ideal environment for viruses, bacteria, fungi and yeast infections. Though most are in denial, we are being overrun by mercury pollution, which is everywhere in the air, water, food, vaccines, dental amalgam and even beauty products. Practitioners are now looking at autism as an issue of both “infections and toxins.” Interestingly doctors involved with the treatment of autism with heavy metal chelation find that when they go after viruses they get heavy metal excretions. When they go after metals they find that they are getting rid of viruses, bacteria, and fungus as well.
Part of our infection fighting arsenal needs to include selenium and ALA (Alpha
Lipoic Acid) and this is critical not only for maintaining glutathione levels but
also for the neutralization of mercury. Alpha Lipoic acid is a potential first
agent for protection from mycotoxins and treatment of mycotoxicosis.8
You cannot treat infectious diseases in effective ways without dealing with the soil of the infection, with the mercury and other chemical toxicities that are driving the pathogens in the first place. A doctor needs to know his poisons but most are in denial of the fact that most pharmaceuticals are mitochondrial poisons. Modern medicine in the United States and a great part of the world is lost when it comes to dealing with mercury and in fact endorses its use in vaccines and dental medicine. Certainly the government does not think it’s worth the effort to control the fifty tons of mercury that come out of its coal fired electrical plants, spilled into the air each year.
Garlic is one food that has powerful anti-bacterial
and anti-fungal properties and some scientific studies
have found it to be at least as effective as the popular
anti-fungal drug, Nystatin, in destroying candida albicans.
In a practical applications chapter called Combining Oral with Transdermal – Dose Sensitivity & Therapeutic Effect, we find that when using nutritional medicines like magnesium chloride, iodine, sodium bicarbonate, vitamin C and alpha Lipoic Acid, the dose does make the effect but in a sense opposite to the allopathic paradigm. In Natural Allopathic Medicine we often take doses to exceedingly high levels without the side effects found in pharmaceuticals that are an ever present danger even at very low dosages.
In allopathic medicine everything, even water and vitamin C are placed on a scale of toxicity with everything being defined as poisonous. And though it’s true, one can drown in water a large person can safely drink a gallon of it a day and one can put pounds of magnesium chloride in one’s bath and take very high dosages of iodine safely for infectious disorders without the serious and dangerous downside of antibiotics.
It is more than possible to cure incurable diseases if we take the right approach that deals with all sides of the equation when one uses the right dosages of iodine, magnesium chloride, sodium bicarbonate, Alpha Lipoic Acid, selenium and vitamin C and this is not an exhaustive list. The key to successful treatment is found in the concentration when using such nutritional medicines, which is the opposite of The Marshall Protocol which follows the allopathic tradition but goes even lower in its use of poisons (antibiotics).
One of the reasons I built the foundation of my medical approach called Natural Allopathic Medicine on transdermal medicine is that transdermal application of magnesium chloride offers the strongest and most effective way that magnesium can be administered safely and economically. Iodine also can be used transdermally for great effect. Transdermal medicine is ideal when treating children because it is easy to administer. With strong therapeutic baths one can load the body not only with magnesium but also with sodium bicarbonate and sodium thiosulfate. Natural Allopathic Medicine stresses nutritional medicine but its main thrust is the use of concentrated nutritional substances that effectively replace most of the dangerous drugs allopathic medicine uses.
With partial legal immunity, Big Pharma has been able to market practically any
poison as a “drug,” regardless of how many people were killed. The Supreme
Court of the United States has just changed all of that making the companies
responsible for damages even if their drugs have been approved by the FDA.
Many decades ago The American Cancer Society said, “Cancer is not caused or cured by any known diet.” Nothing has changed in all these years and the American Diabetes Association maintains a similar position with diabetes. This pathology of wrongness gets expressed by attacking the use of vitamin and mineral supplements and the attack takes the form of publications in the medical media about studies that use dosages that are way too low for therapeutic affect. Codex and major medical organizations are conspiring to keep vitamin and mineral dosages to a minimum when in fact they should be maximized.
We can more easily see now why modern medicine has not been able to cure any chronic disease even with hundreds of billions of dollars in misplaced research. In the case of cancer and diabetes it has been blind to the infectious side of the question. And because the medical industrial complex uses heavy metals like mercury it remains blind to low levels of toxicity from metals, chemicals, drugs and even ionizing radiation, which are used in many of its testing procedures and in cancer treatment.
It is truly sad that modern medicine has turned its back on iodine and tragic that one of its most powerful and effective emergency room medicines for cardiac arrest and stroke, magnesium chloride, continues to be ignored in the treatment of chronic diseases. Even sodium bicarbonate, an extraordinarily effective antifungal used constantly with chemo therapy is ignored for the powerful medicine it actually is. Certain doctors like Dr. Burt Berkson, licensed by the FDA to study intravenous use of ALA understand how it can be used when concentrated.
Click on the books for information.
I wrote and published my Survival Medicine for the 21st Century compendium a few years ago because we are living in an era of great medical challenge that sees a large percentage of humanity falling victims to chronic diseases. We cannot take survival for granted anymore and with the present financial and economic collapse ready to break the back of modern medicine as well as modern civilization we cannot afford expensive medical treatments that are ineffective and dangerous.
Now I am publishing Natural Allopathic Medicine, which explains to professionals and patients alike the basic principles and practices that are expressed in many of my other published and soon to be published books on diabetes and pediatrics. I have been as quickly as possible stepping down the 2,500 pages of Survival Medicine into digestible and more polished finished forms that addresses the more specific needs of practitioners and patients to more effectively and safely confront both chronic and acute illness. A great advantage for all practitioners of my medical approach is that it uses common substances that are easily purchased without prescription, substances used for many common purposes so they will not be easily controlled by Codex or anyone else.
Mark Sircus Ac., OMD
Director International Medical Veritas Association
Professor Sircus (honorary doctor of Oriental medicine) is the Director of Natural Allopathic and Oriental Medical studies at the DaVinci College of Holistic Medicine, which is accredited by the Complementary Medicine Association in the United Kingdom and a member of the International Association for Distance Learning.
Click on the books for information.
2 Dr. John Jacob Cannell writes about the Marshall Protocol: It is true that in some diseases, high doses of vitamin D may be harmful. For example, in the early part of last century, the AMA specifically excluded pulmonary TB from the list of TB infections that ultraviolet light helps. They did so because many of the early pioneers of solariums reported that acutely high doses of sunlight caused some patients with severe pulmonary TB to bleed to death. Thus, these pioneers developed very conservative sun exposure regimes for pulmonary TB patients in which small areas of the skin were progressively exposed to longer and longer periods of sunlight. Using this method, sunlight helped pulmonary TB, often to the point of a cure. Furthermore, it is well known that sunlight can cause high blood calcium in patients with sarcoidosis. In fact, sarcoidosis is one of several granulomatous diseases with vitamin D hypersensitivity where the body loses its ability to regulate activated vitamin D production, causing hypercalcemia. Cronin CC, et al. Precipitation of hypercalcaemia in sarcoidosis by foreign sun holidays: report of four cases. Postgrad Med J. 1990 Apr;66(774):307–9.
Furthermore, although medical science is not yet convinced, some common autoimmune diseases may have an infectious etiology. I recently spoke at length with a rheumatologist who suffers from swollen and painful joints whenever he sunbathes or takes high doses of vitamin D. As long as he limits his vitamin D input his joints are better. To the extent vitamin D upregulates naturally occurring antibiotics of innate immunity, sunlight or vitamin D supplements may cause the battlefield (the joints) to become hot spots. I know of no evidence this is the case but it is certainly possible.
However, if Dr. Marshall’s principal hypothesis is correct, that low vitamin D levels are the result of disease, then he is saying that cancer causes low vitamin D levels, not the other way around. The problem is that Professor Joanne Lappe directly disproved that theory in a randomized controlled trial when she found that baseline vitamin D levels were strong and independent predictors of who would get cancer in the future. The lower your levels, the higher the risk. Furthermore, increasing baseline levels from 31 to 38 ng/ml reduced incident cancers by more than 60% over a four year period. Therefore, advising patients to become vitamin D deficient, as the Marshall protocol clearly does, will cause some patients to die from cancer. Lappe JM, Travers-Gustafson D, Davies KM, Recker RR, Heaney RP. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr. 2007 Jun;85(6):1586–91.
3 Wolf P et al. Phenotypic markers, sunlight-related factors and sunscreen use in patients with cutaneous melanoma: an Austrian case-control study. Melanoma Res. 1998 Aug;8(4):370-8.
5 Abraham GE. “The importance of magnesium in the management of primary postmenopausal osteoporosis.” J Nut Med, 1991; 2:165-178.
6 Bioactive vitamin D or calcitriol is a steroid hormone that has long been known for its important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. More recently, it has become clear that receptors for vitamin D are present in a wide variety of cells, and that this hormone has biologic effects which extend far beyond control of mineral metabolism.
8 Rogers SA. Northeast Center for Environmental Medicine, Sarasota, Florida. Arch Environ Health. 2003 Aug;58(8):528-32.
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©2008 by Mark Sircus